Scientists find something good about a big bottom (Reuters)
They said subcutaneous fat, or fat that collects under the skin, helped to improve sensitivity to the hormone insulin, what one. regulates kin flatter.
Mice that got transplants of this type of fat deep into their abdomens lost ponderosity and their fat cells shrank, even nevertheless they made no changes in their diet or activity levels.
"It was a remarkable result," said Dr. Ronald Kahn of Harvard Medical School in Boston, whose study appears in the journal Cell Metabolism.
"We positively found it had a beneficial truth, and it was especially true whenever you put it inside the abdomen," Kahn said in a telephone interview.
Kahn said he started the study to find out why fat located in dissimilar parts of the body seems to have divergent risks of metabolic disease such as diabetes.
Researchers have known for some span that fat that collects in the visceral cavity — known as visceral fat — be possible to raise a person's risk of diabetes and heart disease, while mob with pear-shaped bodies, with fat deposits in the buttocks and hips, are smaller prone to these disorders.
Now it turns out that subcutaneous fat — fat set up just under the skin — may be actively protecting people from metabolic disease.
Kahn and colleagues conducted a series of experiments on mice where they transplanted subcutaneous fat from donor mice into the bellies and subordinate to the skin of mice.
Mice that got subcutaneous plump transplanted into their bellies started to weak down in the rear of manifold weeks, and they also showed improved blood sweeten and insulin levels compared to mice that underwent a sham procedure.
"What we found was that when we put it in either place, there was some improvement in metabolism," Kahn said.
"I think it's an important result because not only does it declaration that not every one of fat is bad, but I venture it points to a special aspect of fat where we need to translate more research," he said.
Kahn's team is working to find the substances produced in subcutaneous fat that provide the benefit by the hope of developing a drug that might copy this effect. Although fat is known to produce several hormones, Kahn said not the least portion of the known hormones appeared to be involved in this process.
"If we have power to make prisoner those (substances), we might have an opportunity to convert them into drugs or use them like guides to help develop drugs," he said.
(Editing by Maggie Fox and Doina Chiacu)
